Insulin’s direct hepatic effect explains the inhibition of glucose production caused by insulin secretion

Insulin can inhibit hepatic glucose production (HGP) by acting directly on the liver as well as indirectly through effects on adipose tissue, pancreas, and brain. While insulin’s indirect effects are indisputable, their physiologic role in the suppression of HGP seen in response to increased insulin...

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Vydáno v:JCI Insight
Hlavní autoři: Edgerton, Dale S., Kraft, Guillaume, Smith, Marta, Farmer, Ben, Williams, Phillip E., Coate, Katie C., Printz, Richard L., O’Brien, Richard M., Cherrington, Alan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358484/
https://ncbi.nlm.nih.gov/pubmed/28352665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91863
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