Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog

Endogenous insulin secretion exposes the liver to three times higher insulin concentrations than the rest of the body. Because subcutaneous insulin delivery eliminates this gradient and is associated with metabolic abnormalities, functionally restoring the physiologic gradient may provide therapeuti...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Edgerton, Dale S., Moore, Mary C., Winnick, Jason J., Scott, Melanie, Farmer, Ben, Naver, Helle, Jeppesen, Claus B., Madsen, Peter, Kjeldsen, Thomas B., Nishimura, Erica, Brand, Christian L., Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392933/
https://ncbi.nlm.nih.gov/pubmed/24947349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0266
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