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Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog

Endogenous insulin secretion exposes the liver to three times higher insulin concentrations than the rest of the body. Because subcutaneous insulin delivery eliminates this gradient and is associated with metabolic abnormalities, functionally restoring the physiologic gradient may provide therapeuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Edgerton, Dale S., Moore, Mary C., Winnick, Jason J., Scott, Melanie, Farmer, Ben, Naver, Helle, Jeppesen, Claus B., Madsen, Peter, Kjeldsen, Thomas B., Nishimura, Erica, Brand, Christian L., Cherrington, Alan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392933/
https://ncbi.nlm.nih.gov/pubmed/24947349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0266
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