Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC

Glioblastomas, which contain stem cell–like glioblastoma stem cells (GSCs), are universally lethal cancers. While neural stem cells (NSCs) are usually quiescent, single-cell studies suggest that proliferating glioblastoma cells reside in the GSC population. Interrogating in silico glioma databases f...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Guoxin, Dong, Zhen, Prager, Briana C., Kim, Leo J.K., Wu, Qiulian, Gimple, Ryan C., Wang, Xiuxing, Bao, Shideng, Hamerlik, Petra, Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483649/
https://ncbi.nlm.nih.gov/pubmed/30779712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126140
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