Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC

Glioblastomas, which contain stem cell–like glioblastoma stem cells (GSCs), are universally lethal cancers. While neural stem cells (NSCs) are usually quiescent, single-cell studies suggest that proliferating glioblastoma cells reside in the GSC population. Interrogating in silico glioma databases f...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Zhang, Guoxin, Dong, Zhen, Prager, Briana C., Kim, Leo J.K., Wu, Qiulian, Gimple, Ryan C., Wang, Xiuxing, Bao, Shideng, Hamerlik, Petra, Rich, Jeremy N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483649/
https://ncbi.nlm.nih.gov/pubmed/30779712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126140
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