Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC

Glioblastomas, which contain stem cell–like glioblastoma stem cells (GSCs), are universally lethal cancers. While neural stem cells (NSCs) are usually quiescent, single-cell studies suggest that proliferating glioblastoma cells reside in the GSC population. Interrogating in silico glioma databases f...

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Publicat a:JCI Insight
Autors principals: Zhang, Guoxin, Dong, Zhen, Prager, Briana C., Kim, Leo J.K., Wu, Qiulian, Gimple, Ryan C., Wang, Xiuxing, Bao, Shideng, Hamerlik, Petra, Rich, Jeremy N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483649/
https://ncbi.nlm.nih.gov/pubmed/30779712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126140
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