CXCR3 regulates CD4(+) T cell cardiotropism in pressure overload–induced cardiac dysfunction

Heart failure (HF) is associated in humans and mice with increased circulating levels of CXCL9 and CXCL10, chemokine ligands of the CXCR3 receptor, predominantly expressed on CD4(+) Th1 cells. Chemokine engagement of receptors is required for T cell integrin activation and recruitment to sites of in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Ngwenyama, Njabulo, Salvador, Ane M., Velázquez, Francisco, Nevers, Tania, Levy, Alexander, Aronovitz, Mark, Luster, Andrew D., Huggins, Gordon S., Alcaide, Pilar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483643/
https://ncbi.nlm.nih.gov/pubmed/30779709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125527
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge