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Sialomucin CD43 regulates T helper type 17 cell intercellular adhesion molecule 1 dependent adhesion, apical migration and transendothelial migration

T helper type 17 lymphocytes (Th17 cells) infiltrate the central nervous system (CNS), induce inflammation and demyelination and play a pivotal role in the pathogenesis of multiple sclerosis. Sialomucin CD43 is highly expressed in Th17 cells and mediates adhesion to endothelial selectin (E‐selectin)...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Velázquez, Francisco E., Anastasiou, Marina, Carrillo‐Salinas, Francisco J., Ngwenyama, Njabulo, Salvador, Ane M., Nevers, Tania, Alcaide, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459779/
https://ncbi.nlm.nih.gov/pubmed/30690734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13047
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