Isolevuglandin-modified Cardiac Proteins Drive CD4+ T Cell Activation in the Heart and Promote Cardiac Dysfunction

BACKGROUND: Despite the well-established association between T cell-mediated inflammation and non-ischemic heart failure (HF), the specific mechanisms triggering T cell activation during the progression of HF and the antigens involved are poorly understood. We hypothesized that myocardial oxidative...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Ngwenyama, Njabulo, Kirabo, Annet, Aronovitz, Mark, Velázquez, Francisco, Carrillo-Salinas, Francisco, Salvador, Ane M., Nevers, Tania, Amarnath, Venkataraman, Tai, Albert, Blanton, Robert M., Harrison, David G., Alcaide, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987774/
https://ncbi.nlm.nih.gov/pubmed/33463362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.051889
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