PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with unremitting extracellular matrix deposition, leading to a distortion of pulmonary architecture and impaired gas exchange. Fibroblasts from IPF patients acquire an invasive phenotype that is essential for progressive fibrosis. Here, we...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Geng, Yan, Liu, Xue, Liang, Jiurong, Habiel, David M., Kulur, Vrishika, Coelho, Ana Lucia, Deng, Nan, Xie, Ting, Wang, Yizhou, Liu, Ningshan, Huang, Guanling, Kurkciyan, Adrianne, Liu, Zhenqiu, Tang, Jie, Hogaboam, Cory M., Jiang, Dianhua, Noble, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482997/
https://ncbi.nlm.nih.gov/pubmed/30763282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125326
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge