Mitogen-activated Protein Kinase–activated Protein Kinase 2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis

Severe pulmonary fibrosis such as idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of extracellular matrix and fibroblast activation. Targeting fibroblast activation has contributed to the development of antifibrotic therapeutics for patients with IPF. Mitogen-activated prote...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Liang, Jiurong, Liu, Ningshan, Liu, Xue, Mena, Jessica Monterrosa, Xie, Ting, Geng, Yan, Huan, Caijuan, Zhang, Yanli, Taghavifar, Forough, Huang, Guanling, Kurkciyan, Adrianne, Barron, Vivian, Jiang, Dianhua, Noble, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348722/
https://ncbi.nlm.nih.gov/pubmed/30130411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0033OC
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