Mitogen-activated Protein Kinase–activated Protein Kinase 2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis

Severe pulmonary fibrosis such as idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of extracellular matrix and fibroblast activation. Targeting fibroblast activation has contributed to the development of antifibrotic therapeutics for patients with IPF. Mitogen-activated prote...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Liang, Jiurong, Liu, Ningshan, Liu, Xue, Mena, Jessica Monterrosa, Xie, Ting, Geng, Yan, Huan, Caijuan, Zhang, Yanli, Taghavifar, Forough, Huang, Guanling, Kurkciyan, Adrianne, Barron, Vivian, Jiang, Dianhua, Noble, Paul W.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348722/
https://ncbi.nlm.nih.gov/pubmed/30130411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0033OC
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