Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis

Dysregulated repair of lung injury often results in lung fibrosis characterized by unremitting deposition of matrix components including the glycosaminoglycan hyaluronan (HA). HA is mainly produced by hyaluronan synthases (HAS) in mesenchymal cells. We previously demonstrated that over-expression of...

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Gepubliceerd in:Matrix Biol
Hoofdauteurs: Li, Yuejuan, Liang, Jiurong, Yang, Ting, Mena, Jessica Monterrosa, Huan, Caijuan, Xie, Ting, Kurkciyan, Adrianne, Liu, Ningshan, Jiang, Dianhua, Noble, Paul W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383204/
https://ncbi.nlm.nih.gov/pubmed/26987798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.03.004
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