Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis

Dysregulated repair of lung injury often results in lung fibrosis characterized by unremitting deposition of matrix components including the glycosaminoglycan hyaluronan (HA). HA is mainly produced by hyaluronan synthases (HAS) in mesenchymal cells. We previously demonstrated that over-expression of...

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Veröffentlicht in:Matrix Biol
Hauptverfasser: Li, Yuejuan, Liang, Jiurong, Yang, Ting, Mena, Jessica Monterrosa, Huan, Caijuan, Xie, Ting, Kurkciyan, Adrianne, Liu, Ningshan, Jiang, Dianhua, Noble, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383204/
https://ncbi.nlm.nih.gov/pubmed/26987798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.03.004
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