Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease. Although the pathogenesis is poorly understood, evidence suggests that genetic and epigenetic alterations, such as DNA methylation, may play a key role. Bone morphogenetic proteins (BMPs) are members of the transforming growth factor...

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Publicado no:Sci Rep
Main Authors: Huan, Caijuan, Yang, Ting, Liang, Jiurong, Xie, Ting, Cheng, Luis, Liu, Ningshan, Kurkciyan, Adrianne, Monterrosa Mena, Jessica, Wang, Chen, Dai, Huaping, Noble, Paul W., Jiang, Dianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595647/
https://ncbi.nlm.nih.gov/pubmed/26442443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14910
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