Mitogen-activated Protein Kinase–activated Protein Kinase 2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis

Severe pulmonary fibrosis such as idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of extracellular matrix and fibroblast activation. Targeting fibroblast activation has contributed to the development of antifibrotic therapeutics for patients with IPF. Mitogen-activated prote...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Liang, Jiurong, Liu, Ningshan, Liu, Xue, Mena, Jessica Monterrosa, Xie, Ting, Geng, Yan, Huan, Caijuan, Zhang, Yanli, Taghavifar, Forough, Huang, Guanling, Kurkciyan, Adrianne, Barron, Vivian, Jiang, Dianhua, Noble, Paul W.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348722/
https://ncbi.nlm.nih.gov/pubmed/30130411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0033OC
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