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Fixed-parameter tractable sampling for RNA design with multiple target structures

BACKGROUND: The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the need for costly wet-lab experiments. RESULTS: We devise a novel approa...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Hammer, Stefan, Wang, Wei, Will, Sebastian, Ponty, Yann
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482512/
https://ncbi.nlm.nih.gov/pubmed/31023239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2784-7
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