A global sampling approach to designing and reengineering RNA secondary structures

The development of algorithms for designing artificial RNA sequences that fold into specific secondary structures has many potential biomedical and synthetic biology applications. To date, this problem remains computationally difficult, and current strategies to address it resort to heuristics and s...

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Bibliografiske detaljer
Main Authors: Levin, Alex, Lis, Mieszko, Ponty, Yann, O’Donnell, Charles W., Devadas, Srinivas, Berger, Bonnie, Waldispühl, Jérôme
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488226/
https://ncbi.nlm.nih.gov/pubmed/22941632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks768
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