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Multi-objective optimization for RNA design with multiple target secondary structures

BACKGROUND: RNAs are attractive molecules as the biological parts for synthetic biology. In particular, the ability of conformational changes, which can be encoded in designer RNAs, enables us to create multistable molecular switches that function in biological circuits. Although various algorithms...

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Pubblicato in:BMC Bioinformatics
Autore principale: Taneda, Akito
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559319/
https://ncbi.nlm.nih.gov/pubmed/26335276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0706-x
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