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pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG

Plasmacytoid dendritic cells (pDCs) express high levels of the toll-like receptors (TLRs) TLR7 and TLR9. In response to TLR7 and TLR9 ligands, pDCs are primary producers of type I interferons. Our previous study demonstrated that pDCs activated by the TLR7 ligand imiquimod (IMQ) and the TLR9 ligand...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Wu, Jing, Li, Shuang, Li, Tete, Lv, Xinping, Zhang, Mingyou, Zang, Guoxia, Qi, Chong, Liu, Yong-Jun, Xu, Liang, Chen, Jingtao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481147/
https://ncbi.nlm.nih.gov/pubmed/31093508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1749803
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