A Novel C Type CpG Oligodeoxynucleotide Exhibits Immunostimulatory Activity In Vitro and Enhances Antitumor Effect In Vivo

BACKGROUND: C type CpG oligodeoxynucleotides (CpG-C ODNs), possessing the features of both A type and B type CpG ODNs, exert a variety of immunostimulatory activities and have been demonstrated as an effective antitumor immunotherapy. Based on the structural characteristics, we designed 20 potential...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Tete, Wu, Jing, Zhu, Shan, Zang, Guoxia, Li, Shuang, Lv, Xinping, Yue, Wenjun, Qiao, Yuan, Cui, Jiuwei, Shao, Yan, Zhang, Jun, Liu, Yong-Jun, Chen, Jingtao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015978/
https://ncbi.nlm.nih.gov/pubmed/32116691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00008
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