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Hierarchical recognition of CpG motifs expressed by immunostimulatory oligodeoxynucleotides

Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs trigger human PBMC to proliferate and secrete Ig, cytokines and chemokines. CpG ODN have entered clinical trials, and show promise as vaccine adjuvants, antiallergens, and for the treatment of infectious diseases and cancer. OD...

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Autori principali: KLINMAN, D M, CURRIE, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808776/
https://ncbi.nlm.nih.gov/pubmed/12869028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02216.x
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