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Hierarchical recognition of CpG motifs expressed by immunostimulatory oligodeoxynucleotides
Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs trigger human PBMC to proliferate and secrete Ig, cytokines and chemokines. CpG ODN have entered clinical trials, and show promise as vaccine adjuvants, antiallergens, and for the treatment of infectious diseases and cancer. OD...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808776/ https://ncbi.nlm.nih.gov/pubmed/12869028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02216.x |
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