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Hierarchical recognition of CpG motifs expressed by immunostimulatory oligodeoxynucleotides

Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs trigger human PBMC to proliferate and secrete Ig, cytokines and chemokines. CpG ODN have entered clinical trials, and show promise as vaccine adjuvants, antiallergens, and for the treatment of infectious diseases and cancer. OD...

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Autors principals: KLINMAN, D M, CURRIE, D
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808776/
https://ncbi.nlm.nih.gov/pubmed/12869028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02216.x
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