Hierarchical recognition of CpG motifs expressed by immunostimulatory oligodeoxynucleotides

Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs trigger human PBMC to proliferate and secrete Ig, cytokines and chemokines. CpG ODN have entered clinical trials, and show promise as vaccine adjuvants, antiallergens, and for the treatment of infectious diseases and cancer. OD...

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Hlavní autoři: KLINMAN, D M, CURRIE, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2003
Témata:
Basic Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808776/
https://ncbi.nlm.nih.gov/pubmed/12869028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02216.x
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