TLR9 Ligand CpG-ODN Applied to the Injured Mouse Cornea Elicits Retinal Inflammation

During bacterial and viral infections, unmethylated CpG-DNA released by proliferating and dying microbes is recognized by toll-like receptor (TLR) 9 in host cells, initiating innate immune responses. Many corneal infections occur secondary to epithelial breaches and represent a major cause of vision...

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Main Authors: Chinnery, Holly R., McLenachan, Samuel, Binz, Nicolette, Sun, Yan, Forrester, John V., Degli-Esposti, Mariapia A., Pearlman, Eric, McMenamin, Paul G.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2012
主題:
Regular Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338340/
https://ncbi.nlm.nih.gov/pubmed/22085974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.09.041
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