Comparison of in vivo Adjuvanticity of Liposomal PO CpG ODN with Liposomal PS CpG ODN: Soluble Leishmania Antigens as a Model

OBJECTIVE(S): CpG oligodeoxynucleotides (CpG ODNs) have been shown to have potent immunostimulatory adjuvant activity for a wide range of antigens. Due to susceptibility of phosphodiester CpG ODNs (PO CpG) to nuclease degradation, nuclease-resistant phosphorothioate CpG ODNs (PS CpG) were currently...

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Hlavní autoři: Golali, Ensieh, Jaafari, Mahmoud Reza, Khamesipour, Ali, Abbasi, Azam, Saberi, Zahra, Badiee, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586918/
https://ncbi.nlm.nih.gov/pubmed/23493437
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