Liposomal gp100 vaccine combined with CpG ODN sensitizes established B16F10 melanoma tumors to anti PD-1 therapy

OBJECTIVE(S): Program death 1 (PD-1)/ program death-ligand 1 (PD-L1) pathways, as the main inhibitory checkpoints, induce immunosuppression in the tumor microenvironment (TME). Despite the importance of inhibitor checkpoint receptor (ICR) blockers, their outcomes have been limited by the low immune...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Yazdani, Mona, Hatamipour, Mahdi, Alani, Behrang, Nikzad, Hossein, Mohamadian Roshan, Nema, Verdi, Javad, Jaafari, Mahmoud Reza, Noureddini, Mahdi, Badiee, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478250/
https://ncbi.nlm.nih.gov/pubmed/32952954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.46654.10762
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