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Ex vivo dendritic cell-based (DC) vaccine pulsed with a low dose of liposomal antigen and CpG-ODN improved PD-1 blockade immunotherapy

Lack of pre-existing tumor infiltrated T cells resulting in resistance to programmed cell death protein 1 (PD-1) blockade therapies can be solved by combining with anti-cancer vaccines and CpG-ODN in increasing T cell expansion and infiltration. Therefore, we prepared an ex vivo dendritic cell-based...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yazdani, Mona, Gholizadeh, Zahra, Nikpoor, Amin Reza, Mohamadian Roshan, Nema, Jaafari, Mahmoud Reza, Badiee, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290007/
https://ncbi.nlm.nih.gov/pubmed/34282215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94250-0
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