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Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice

BACKGROUND: To overcome infectious diseases, the development of mucosal vaccines would be an effective strategy, since mucosal surfaces are the entry site for most pathogens. In general, protein antigens show inherently poor immunogenicity when administered by the mucosal route. Therefore, co-admini...

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Dades bibliogràfiques
Publicat a:BMC Res Notes
Autors principals: Tada, Rui, Muto, Shoko, Iwata, Tomoko, Hidaka, Akira, Kiyono, Hiroshi, Kunisawa, Jun, Aramaki, Yukihiko
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270218/
https://ncbi.nlm.nih.gov/pubmed/28126014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2380-8
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