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Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice

BACKGROUND: To overcome infectious diseases, the development of mucosal vaccines would be an effective strategy, since mucosal surfaces are the entry site for most pathogens. In general, protein antigens show inherently poor immunogenicity when administered by the mucosal route. Therefore, co-admini...

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Dettagli Bibliografici
Pubblicato in:BMC Res Notes
Autori principali: Tada, Rui, Muto, Shoko, Iwata, Tomoko, Hidaka, Akira, Kiyono, Hiroshi, Kunisawa, Jun, Aramaki, Yukihiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270218/
https://ncbi.nlm.nih.gov/pubmed/28126014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2380-8
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