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Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice

BACKGROUND: To overcome infectious diseases, the development of mucosal vaccines would be an effective strategy, since mucosal surfaces are the entry site for most pathogens. In general, protein antigens show inherently poor immunogenicity when administered by the mucosal route. Therefore, co-admini...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Tada, Rui, Muto, Shoko, Iwata, Tomoko, Hidaka, Akira, Kiyono, Hiroshi, Kunisawa, Jun, Aramaki, Yukihiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270218/
https://ncbi.nlm.nih.gov/pubmed/28126014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-017-2380-8
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