Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

CRISPR-Cas immune systems utilize RNA-guided nucleases to protect bacteria from bacteriophage infection. Bacteriophages have in turn evolved inhibitory “anti-CRISPR” (Acr) proteins, including six inhibitors (AcrIIA1–AcrIIA6) that can block DNA cutting and genome editing by type II-A CRISPR-Cas9 enzy...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Cell
Hoofdauteurs: Jiang, Fuguo, Liu, Jun-Jie, Osuna, Beatriz A., Xu, Michael, Berry, Joel D., Rauch, Benjamin J., Nogales, Eva, Bondy-Denomy, Joseph, Doudna, Jennifer A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480404/
https://ncbi.nlm.nih.gov/pubmed/30595438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.016
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items