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Temperature-Responsive Competitive Inhibition of CRISPR-Cas9
CRISPR-Cas immune systems utilize RNA-guided nucleases to protect bacteria from bacteriophage infection. Bacteriophages have in turn evolved inhibitory “anti-CRISPR” (Acr) proteins, including six inhibitors (AcrIIA1–AcrIIA6) that can block DNA cutting and genome editing by type II-A CRISPR-Cas9 enzy...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6480404/ https://ncbi.nlm.nih.gov/pubmed/30595438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.11.016 |
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