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The Structural Biology of CRISPR-Cas Systems

Prokaryotic CRISPR-Cas genomic loci encode RNA-mediated adaptive immune systems that bear some functional similarities with eukaryotic RNA interference. Acquired and heritable immunity against bacteriophage and plasmids begins with integration of ~30 base pair foreign DNA sequences into the host gen...

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Bibliografski detalji
Izdano u:Curr Opin Struct Biol
Glavni autori: Jiang, Fuguo, Doudna, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417044/
https://ncbi.nlm.nih.gov/pubmed/25723899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.02.002
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