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In Vitro and In Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

Protein kinase CK2 is an emerging target for therapeutic intervention in human diseases, particularly in cancer. Inhibitors of this enzyme are currently in clinical trials, indicating the druggability of human CK2. By virtual screening of the ZINC database, we found that the natural compound bikaver...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Molecules
Egile Nagusiak: Haidar, Samer, Aichele, Dagmar, Birus, Robin, Hielscher, Janine, Laitinen, Tuomo, Poso, Antti, Jose, Joachim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479664/
https://ncbi.nlm.nih.gov/pubmed/30965682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24071380
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