Hypoxia-inducible factor 2α: a novel target in gliomas

Hypoxia is an important contributor to aggressive behavior and resistance mechanisms in glioblastoma. Upregulation of hypoxia inducible transcription factors (HIFs) is the primary adaptive cellular response to a hypoxic environment. While HIF1α has been widely studied in cancer, HIF2α offers a poten...

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Vydáno v:Future Med Chem
Hlavní autoři: Renfrow, Jaclyn J, Soike, Michael H, Debinski, Waldemar, Ramkissoon, Shakti H, Mott, Ryan T, Frenkel, Mark B, Sarkaria, Jann N, Lesser, Glenn J, Strowd, Roy E
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Science Ltd 2018
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479274/
https://ncbi.nlm.nih.gov/pubmed/30089425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0163
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