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Hypoxia-inducible factor 2α: a novel target in gliomas
Hypoxia is an important contributor to aggressive behavior and resistance mechanisms in glioblastoma. Upregulation of hypoxia inducible transcription factors (HIFs) is the primary adaptive cellular response to a hypoxic environment. While HIF1α has been widely studied in cancer, HIF2α offers a poten...
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| Publicat a: | Future Med Chem |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Future Science Ltd
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6479274/ https://ncbi.nlm.nih.gov/pubmed/30089425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0163 |
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