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Hypoxia-inducible factor 2α: a novel target in gliomas

Hypoxia is an important contributor to aggressive behavior and resistance mechanisms in glioblastoma. Upregulation of hypoxia inducible transcription factors (HIFs) is the primary adaptive cellular response to a hypoxic environment. While HIF1α has been widely studied in cancer, HIF2α offers a poten...

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Publicat a:Future Med Chem
Autors principals: Renfrow, Jaclyn J, Soike, Michael H, Debinski, Waldemar, Ramkissoon, Shakti H, Mott, Ryan T, Frenkel, Mark B, Sarkaria, Jann N, Lesser, Glenn J, Strowd, Roy E
Format: Artigo
Idioma:Inglês
Publicat: Future Science Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479274/
https://ncbi.nlm.nih.gov/pubmed/30089425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0163
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