Hypoxia-inducible factor 2α: a novel target in gliomas

Hypoxia is an important contributor to aggressive behavior and resistance mechanisms in glioblastoma. Upregulation of hypoxia inducible transcription factors (HIFs) is the primary adaptive cellular response to a hypoxic environment. While HIF1α has been widely studied in cancer, HIF2α offers a poten...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Renfrow, Jaclyn J, Soike, Michael H, Debinski, Waldemar, Ramkissoon, Shakti H, Mott, Ryan T, Frenkel, Mark B, Sarkaria, Jann N, Lesser, Glenn J, Strowd, Roy E
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6479274/
https://ncbi.nlm.nih.gov/pubmed/30089425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0163
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