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2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice

Aryl hydrocarbon receptor (AhR) activation is reported to alter the hepatic expression of circadian clock regulators, however the impact on clock-controlled metabolism has not been thoroughly investigated. This study examines the effects of AhR activation on hepatic transcriptome and metabolome rhyt...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Fader, Kelly A., Nault, Rance, Doskey, Claire M., Fling, Russell R., Zacharewski, Timothy R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478849/
https://ncbi.nlm.nih.gov/pubmed/31015483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42760-3
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