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MEDU-39. HIGHLY RECURRENT U1 SMALL NUCLEAR RNA HOTSPOT MUTATIONS DRIVE ALTERNATIVE SPLICING IN SONIC HEDGEHOG MEDULLOBLASTOMA
Recurrent somatic single nucleotide variants (SNVs) in cancer are largely confined to protein-coding genes, and are rare in pediatric cancers. Similar to many pediatric cancers, medulloblastomas harbor few recurrent somatic SNVs except for TERT promoter mutations. To investigate non-coding mutations...
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| Publicat a: | Neuro Oncol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477429/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.197 |
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