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MEDU-46. SONIC HEDGEHOG SPEEDS UP DNA REPLICATION AND CAUSES CANCER-INITIATING MUTATIONS
Cancer is a multi-stage disease caused by sequential mutations; however, the molecular mechanism that generates cancer-initiating mutations is not well understood. Using the developing cerebellum as a model system, here we show the molecular mechanism of tumor initiation in Sonic hedgehog medullobla...
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| Publicado no: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477353/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.204 |
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