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MEDU-11. SONIC HEDGEHOG AND REACTIVE OXYGEN SPECIES INTERACT TO REGULATE MITOCHONDRIAL MORPHOLOGY IN MEDULLOBLASTOMA
Sonic hedgehog (Shh) signaling is closely coupled with the bioenergetics of medulloblastoma, the most common malignant pediatric solid tumor. We have reported earlier that Shh causes deregulation of mitochondrial biogenesis by suppressing mitofusins, leading to fragmented mitochondria in vitro as we...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475135/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.162 |
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