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HGG-22. CHARACTERIZING THE ROLE H3.3G34R MUTATION IN PEDIATRIC HIGH GRADE ASTROCYTOMA
PURPOSE: Approximately 20% of hemispheric pHGA have a mutation in the histone H3.3 encoding H3F3A gene, leading to a glycine-arginine substitution (H3.3G34R). However, our understanding of the biological consequences of this mutation remain poor. Here we use a novel proteomics-based strategy to inve...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477418/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.116 |
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