DIPG-23. EFFICACY OF THE SOLUBLE PANOBINOSTAT (MTX110) IN PRECLINICAL DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MODELS

INTRODUCTION: Large drug screening and preclinical studies identified the pan-histone deacetylate inhibitor panobinostat as a promising treatment for DIPG. However, blood brain barrier functional integrity in DIPG limits drug penetration and remains a key cause of resistance to therapies. Therefore,...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Truffaux, Nathalene, Yang, Xiaodong, Hadaczek, Piotr, Bankiewicz, Krystof, Damment, Stephen J P, Mueller, Sabine
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Diffuse Intrinsic Pontine Glioma (DIPG)
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477314/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.044
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki