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DIPG-29. DFMO AND PANOBINOSTAT TARGET LIN28 AND HDAC IN DIPG DECREASING CELL VIABILITY

BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is an aggressive pediatric cancer with a poor prognosis of < 10% overall survival at 2 years from diagnosis. Due to their location DIPG presents a therapeutic challenge with radiation as the mainstay of therapy. Over 80% of DIPG tumors harbor a...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Maser, Tyler, Zagorski, Joseph, VanSickle, Elizabeth, Nagulapally, Abhinav, Sholler, Giselle Saulnier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477234/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.050
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