ETMR-18. TARGETING Lin28 IN ETMR WITH ODC1 INHIBITOR DFMO

Embryonal tumor with multilayered rosettes (ETMR), is an aggressive brain tumor primarily occurring in young patients (<4 years of age) and characterized by C19MC amplification and Lin28 overexpression. These genetic hallmarks have been shown to participate in driving ETMR in a C19MC-Lin28-MYCN c...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Goodyke, Austin, Kelly, Shannon, Zagorski, Joseph, VanSickle, Elizabeth, Maser, Tyler, Sortwell, Caryl, Kemp, Christopher, Nagulapally, Abhinav, Dykema, Karl, Saulnier-Sholler, Giselle
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
ETMR and other Embryonal Tumors
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715939/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.221
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