DIPG-12. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs)

Diffuse Intrinsic Pontine Gliomas (DIPGs) are universally fatal. Effective treatments are desperately needed. DIPGs harbor histone K27M mutations (H3F3A or HIST1H3B) and also alterations that lead to growth factor receptor activation (such as PDGFRA amplification). We and others have found recurrent...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Khadka, Prasidda, Reitman, Zachary J, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Stiles, Charles D, Chowdhury, Dipanjan, Haas-Kogan, Daphne, Johannessen, Cory, Ebert, Benjamin L, Ligon, Keith L, Phoenix, Timothy, Beroukhim, Rameen, Bandopadhayay, Pratiti
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
Diffuse Intrinsic Pontine Glioma (DIPG)
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477302/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.033
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים