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OMRT-6. Optimizing MDM2 inhibition for the treatment of high-grade glioma
Over 80% of high-grade gliomas have alterations in members of the p53 pathway, a central regulator of cell cycle progression and apoptosis that becomes activated in response to cellular stress and DNA damage. For tumors that retain wild-type p53, pathway deregulation frequently occurs through the am...
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| Publicado no: | Neurooncol Adv |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8255430/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab070.031 |
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