LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY

Pediatric low-grade gliomas (PLGGs) are slow growing tumors that result in neurologic defects due to both disease burden and therapeutic complications. We have previously performed FFPE bulk expression profiling on more than 150 PLGGs that revealed substantial tumor heterogeneity on the level of gen...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Paolella, Brenton, Bandopadhayay, Pratiti, Bergthold, Guillaume, Shalek, Alex, Pelton, Kristine, Ramkissoon, Shakti, Sinai, Claire, Malkin, Hayley, Herbert, Zach, Sun, Yu, Alberta, John, Brown, Meredith, Daley, John, Lazo-Kallanian, Suzan, Goumnerova, Liliana, Kieran, Mark, Ligon, Keith, Beroukhim, Rameen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475120/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.138
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