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LGG-06. FUNCTIONAL AND THERAPEUTIC RELEVANCE OF MYB-QKI-INDUCED TRANSCRIPTIONAL EVENTS TO GLIOMAGENESIS
INTRODUCTION: The large-scale genomic analysis of pediatric low-grade gliomas recently conducted in our laboratories identified the MYB-QKI fusion as a genetic driver of angiocentric glioma. MYB-QKI retains the MYB HTH DNA-binding domain and functions as a transcription factor. These findings presen...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475125/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.139 |
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