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DIPG-24. DIFFUSE INTRINSIC PONTINE GLIOMAS EXHIBIT HIGH BASAL DNA DAMAGE AND ARE VULNERABLE TO INHIBITION OF DNA DAMAGE REPAIR PATHWAYS
BACKGROUNDL Diffuse intrinsic pontine gliomas (DIPGs) are fatal childhood gliomas and radiotherapy is the only modality that prolongs survival; however, all patients progress with no long term survivors, indicating an urgent need to develop new treatment approaches. METHODS: Genome wide CRISPR scree...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477259/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.045 |
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