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DIPG-24. DIFFUSE INTRINSIC PONTINE GLIOMAS EXHIBIT HIGH BASAL DNA DAMAGE AND ARE VULNERABLE TO INHIBITION OF DNA DAMAGE REPAIR PATHWAYS
BACKGROUNDL Diffuse intrinsic pontine gliomas (DIPGs) are fatal childhood gliomas and radiotherapy is the only modality that prolongs survival; however, all patients progress with no long term survivors, indicating an urgent need to develop new treatment approaches. METHODS: Genome wide CRISPR scree...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477259/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.045 |
| タグ: |
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