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DIPG-37. THE KETONE BODY β-HYDROXYBUTYRATE ACTS AS AN EPIGENETIC MODIFIER AND INCREASES RADIATION-INDUCED DNA DAMAGE IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse Intrinsic Pontine Glioma (DIPG) is a highly infiltrative pediatric tumor with a median survival of approximately 9 months. Due to its location, the tumor is generally considered inoperable and there are few therapeutic options. Radiation is the only primary treatment for these tumors; howeve...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Rossi, Alex P, Syed, Nelofer, Wetmore, Cynthia, Scheck, Adrienne C
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.058
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