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DIPG-37. THE KETONE BODY β-HYDROXYBUTYRATE ACTS AS AN EPIGENETIC MODIFIER AND INCREASES RADIATION-INDUCED DNA DAMAGE IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse Intrinsic Pontine Glioma (DIPG) is a highly infiltrative pediatric tumor with a median survival of approximately 9 months. Due to its location, the tumor is generally considered inoperable and there are few therapeutic options. Radiation is the only primary treatment for these tumors; howeve...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Rossi, Alex P, Syed, Nelofer, Wetmore, Cynthia, Scheck, Adrienne C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477371/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.058
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